OLIS RSM 1000用于雜化細菌視紫紅質/量子點體系的可調諧光循環動力學研究
Tunable photocycle kinetics of a hybrid bacteriorhodopsin/quantum dot system

在生物環境中包含無機納米粒子已導致產生用于各種應用的混合納米系統。一種這樣的系統包括與光活性蛋白質細菌視紫紅質（BR）偶聯的量子點（QD），其已經在開發增強型光伏器件中進行了探索。在這項工作中，我們發現可以使用CdSe / CdS（核/殼）QD來控制BR光循環的動力學。使用時間分辨吸收光譜法監測具有不同QD量的蛋白質樣品的光循環壽命。在動力學跡線中觀察到bR和M狀態壽命的濃度依賴性伸長，因此表明BR和QD之間發生激子耦合。我們提出BR與QD的配對有可能用于基于蛋白質的計算應用，特別是用于實時全息處理器，其依賴于bR和M光中間體的時間動態。

The inclusion of inorganic nanoparticles in biological environments has led to the creation of hybrid nanosystems that are employed in a variety of applications. One such system includes quantum dots (QDs) coupled with the photoactive protein, bacteriorhodopsin (BR), which has been explored in developing enhanced photovoltaic devices. In this work, we have discovered that the kinetics of the BR photocycle can be manipulated using CdSe/CdS (core/shell) QDs. The photocycle lifetime of protein samples with varying QD amounts were monitored using time-resolved absorption spectroscopy. Concentration-dependent elongations of the bR and M state lifetimes were observed in the kinetic traces, thus suggesting that excitonic coupling occurs between BR and QDs. We propose that the pairing of BR with QDs has the potential to be utilized in protein-based computing applications, specifically for real-time holographic processors, which depend on the temporal dynamics of the bR and M photointermediates.

https://link.springer.com/article/10.1007/s12274-018-2224-4